China 2003a.
Methods | Randomised controlled trial. | |
Participants | 156 women in labour who gave birth without complications via the birth canal and had no coagulation disorders or contraindications regarding the use of misoprostol. | |
Interventions | Oral 200 mcg dose of misoprostol immediately after delivery and another 200 mcg after 60 minutes versus no medication (a total of 400 mcg). | |
Outcomes | Haemorrhage occurrence rate, amount 2 hours after delivery and side‐effects. | |
Notes | No mention of active management of third stage labour. Blood loss was measured based on volume and weight. |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Unclear how the sequence generation was done. |
Allocation concealment (selection bias) | Unclear risk | Unclear how the allocation concealment was done. |
Blinding (performance bias and detection bias) All outcomes | Unclear risk | Unclear on blinding. |
Incomplete outcome data (attrition bias) All outcomes | Low risk | No mention of loss to follow‐up or postrandomisation exclusions. |
Selective reporting (reporting bias) | Unclear risk | Not all of the primary outcomes of the review were reported. |
Other bias | Low risk | 2 groups were comparable. |