Skip to main content
. 2012 Aug 15;2012(8):CD000494. doi: 10.1002/14651858.CD000494.pub4

China 2003a.

Methods Randomised controlled trial.
Participants 156 women in labour who gave birth without complications via the birth canal and had no coagulation disorders or contraindications regarding the use of misoprostol.
Interventions Oral 200 mcg dose of misoprostol immediately after delivery and another 200 mcg after 60 minutes versus no medication (a total of 400 mcg).
Outcomes Haemorrhage occurrence rate, amount 2 hours after delivery and side‐effects.
Notes No mention of active management of third stage labour.
Blood loss was measured based on volume and weight.
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Unclear how the sequence generation was done.
Allocation concealment (selection bias) Unclear risk Unclear how the allocation concealment was done.
Blinding (performance bias and detection bias) 
 All outcomes Unclear risk Unclear on blinding.
Incomplete outcome data (attrition bias) 
 All outcomes Low risk No mention of loss to follow‐up or postrandomisation exclusions.
Selective reporting (reporting bias) Unclear risk Not all of the primary outcomes of the review were reported.
Other bias Low risk 2 groups were comparable.