China 2003b.

Methods	Randomised controlled trial.
Participants	137 women with risk factors for postpartum haemorrhage such as placenta previa, polyhydramnios, macrosomia, twin pregnancy and pregnancy‐induced hypertension. Control group had 28 women who had caesarean sections. No exclusion criteria specified.
Interventions	400 mcg oral misoprostol versus 20 IU IM oxytocin immediately after the delivery of the baby.
Outcomes	Amount of bleeding after delivery, blood pressure and pulse before and after taking the medication, side‐effects.
Notes	AMSTL not mentioned and not applicable to caesarean section patients in the control group. Volume was measured with a blood collection drape until 2 hours after delivery, then poured into a scaled bottle to measure the volume. For caesarean patients, the volume of blood was directly measured in the suction bottle (after putting it aside all the visible amniotic fluid above the cleared blood was discarded and not counted). The weighing method for bleeding 2 hours after delivery used the dressings before and after which were weighed separately. The estimation method used surgical single contaminated blood stain range of 10 cm X 10 cm equals 5 mL blood estimation. The 3 methods mentioned above were added up to be the total amount of blood lost 2 hours after delivery. For 24 hours after delivery a paper pad was used to absorb vaginal bleeding, and then the weighing method was used to calculate the blood loss. Then finally added up the total amount of bleeding 24 hours after delivery.
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Not clear on how the sequence generation was done.
Allocation concealment (selection bias)	Unclear risk	Unclear on how the allocation concealment was done.
Blinding (performance bias and detection bias) All outcomes	Unclear risk	Unclear on the blinding.
Incomplete outcome data (attrition bias) All outcomes	Low risk	No loss to follow‐up or postrandomisation exclusions were mentioned.
Selective reporting (reporting bias)	Unclear risk	Not all of the primary outcomes of the review were reported.
Other bias	Unclear risk	General comparison of the 2 groups showed that there was no significant difference in age and gestational week, however, there are 28 caesarean sections in the control group only.