| Methods |
Open, randomised trial. Randomisation generated by a random‐number table. Unclear if outcome assessments were blinded. |
| Participants |
60 low‐risk women delivering vaginally in Hong Kong, China. |
| Interventions |
Misoprostol 600 mcg sublingually vs syntometrine IV. |
| Outcomes |
Blood loss, side‐effects. Blood loss was both estimated visually and measured using alkaline hematin technique. |
| Notes |
Third stage management was 'active' using early cord clamping and cord traction. |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Random sequence generation (selection bias) |
Low risk |
"Random number‐generated table." |
| Allocation concealment (selection bias) |
High risk |
Inadequate concealment. |
| Blinding (performance bias and detection bias)
All outcomes |
High risk |
Open trial. Unclear if outcome assessments are blinded. |
| Incomplete outcome data (attrition bias)
All outcomes |
Low risk |
No mention of postrandomisation exclusion or loss to follow‐up. |
| Selective reporting (reporting bias) |
Unclear risk |
Not all of the primary outcomes of the review have been reported. |
| Other bias |
Low risk |
Demographic and labour characteristics of the 2 groups are comparable. |
