Methods |
Randomised trial. No further details. Unclear if outcome assessments were blinded. |
Participants |
120 women with at least 1 risk factor for atonic haemorrhage at Jawaharial Institute of Medical Education and Research Hospital in Pondicherry, India. |
Interventions |
Group A: methylergometrine 0.2 mg IV.
Group B: oxytocin 10 IU in 10 mL saline into the umbilical cord.
Group C: carboprost 0.250 mg IM. |
Outcomes |
Blood loss, side‐effects. Blood loss measurement not mentioned. |
Notes |
Management of third stage: 'active' with controlled cord traction following signs of separation. No loss to follow‐up. |
Risk of bias |
Bias |
Authors' judgement |
Support for judgement |
Random sequence generation (selection bias) |
Unclear risk |
No mention of sequence generation. |
Allocation concealment (selection bias) |
Unclear risk |
No mention of allocation concealment. |
Blinding (performance bias and detection bias)
All outcomes |
Unclear risk |
Unclear if outcome assessments were blinded. |
Incomplete outcome data (attrition bias)
All outcomes |
Low risk |
No loss to follow‐up or exclusion after randomisation was mentioned. |
Selective reporting (reporting bias) |
Unclear risk |
Not all of the primary outcomes of the review were reported. |
Other bias |
Unclear risk |
No mention of comparability of the groups. |