| Methods |
Random allocation, no further details. Unclear if outcome assessments were blinded. |
| Participants |
200 primiparous women with singleton births at Lok Nayak Hospital, New Delhi, India. |
| Interventions |
Misoprostol 600 mcg orally immediately after delivery vs 0.2 mg methylergometrine IV at delivery of anterior shoulder. |
| Outcomes |
Blood loss, side‐effects. Blood loss measurement method not mentioned. |
| Notes |
Management of the third stage: early cord clamping but no mention of placental delivery. No mention of missing data or loss to follow‐up. |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Random sequence generation (selection bias) |
Unclear risk |
"1:1 ratio by random number sequence." |
| Allocation concealment (selection bias) |
Unclear risk |
Unclear how the allocation concealment was done. |
| Blinding (performance bias and detection bias)
All outcomes |
Unclear risk |
Unclear if outcome assessments were blinded. |
| Incomplete outcome data (attrition bias)
All outcomes |
Low risk |
No mention of loss to follow‐up or exclusion after randomisation. |
| Selective reporting (reporting bias) |
Unclear risk |
Not all of the primary outcomes of the review were reported. |
| Other bias |
Unclear risk |
The information on the comparability of 2 groups were not provided. |
