India 2006f.

Methods	Randomised, placebo‐controlled study.
Participants	200 women in spontaneous labour. No exclusion criteria were reported.
Interventions	600 mcg rectal misoprostol versus 10 IU IM oxytocin.
Outcomes	Estimated blood loss (mL), blood loss ≥ 500 mL, change in Hb (g/dL), length of third stage of labour (min), need for additional oxytocic drugs, need for manual removal of placenta and side‐effects (shivering, nausea, temperature ≥ 38 C)
Notes	Active management of third stage of labour. Blood loss was measured by using calibrated drapes (BRASSS‐V drape) and using preweighted gauzes to clean the perineal tears and episiotomy.
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	"computer generated random tables."
Allocation concealment (selection bias)	Low risk	"sealed envelope with a code number was opened when vaginal delivery was imminent."
Blinding (performance bias and detection bias) All outcomes	Low risk	Double‐blinded. The code was not broken until the end of the study.
Incomplete outcome data (attrition bias) All outcomes	Low risk	No losses to follow‐up or postrandomisation exclusions were reported.
Selective reporting (reporting bias)	Low risk	All of the outcomes were reported.
Other bias	Low risk	The 2 groups were similar with regards to baseline characteristics.