India 2006g.
Methods | Randomised controlled trial. | |
Participants | 200 women with singleton pregnancy, spontaneous onset of labour at term and vertex presentation admitted in active phase of labour were included. Women with hypertension, cardiac disease, renal disease, gastrointestinal disorders, respiratory disease, endocrinal problems, coagulation disorder, and sensitivity to prostaglandin or methergin were excluded. |
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Interventions | 125 mcg IM PGF2 versus 0.2 mg methergin IV at the time of the anterior shoulder delivery. | |
Outcomes | Duration of third stage, blood loss, need for additional drugs, retained placenta and side‐effects (nausea and vomiting). | |
Notes | Active management of third stage of labour. Blood loss was estimated by blood and blood clots collected in the kidney tray. |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | "random number tables." |
Allocation concealment (selection bias) | Unclear risk | Unclear on how the allocation concealment was done. |
Blinding (performance bias and detection bias) All outcomes | Unclear risk | Not clear on if the blinding occurred. |
Incomplete outcome data (attrition bias) All outcomes | Low risk | No loss to follow‐up and exclusions after randomisation were reported. |
Selective reporting (reporting bias) | Unclear risk | Not all of the primary outcomes of the review were reported. |
Other bias | Low risk | The 2 groups were well matched in the baseline. |