India 2009d.

Methods	Randomised controlled trial.
Participants	200 pregnant women at ≥ 32 weeks of gestation with either spontaneous or induced labour (what authors identified as low‐risk) were included. Exclusion criteria included grandmultipara (≥ 5), multiple gestation, < 32 weeks of gestation, HELLP syndrome, hydramnios, known blood coagulation disorders, history of asthma or drug allergy, heart disease, severe renal disease, epilepsy, hypertension and haemoglobin concentration < 8 g%.
Interventions	400 mcg sublingual misoprostol versus 0.2 mg IM methylergometrine
Outcomes	Primary outcome measures were amount of blood loss in third stage of labour, postpartum haemorrhage (blood loss greater than 500 mL). Secondary outcome measures were change in haemoglobin concentration, need for additional oxytocic and side‐effects (nausea, temperature ≥ 38 C, shivering, pain in the abdomen and diarrhoea).
Notes	Active management of third stage of labour. Blood loss was estimated by measuring blood collected in the BRASS‐V drape, up to 1 hour after delivery of the baby, and blood soaked in gauze pieces. Blood loss in gauze pieces was calculated by subtracting weight of dry gauze from the weight of blood‐soaked gauze pieces.
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	"computer‐generated random number."
Allocation concealment (selection bias)	Unclear risk	Unclear on how the allocation concealment was done.
Blinding (performance bias and detection bias) All outcomes	Unclear risk	Not clear on blinding.
Incomplete outcome data (attrition bias) All outcomes	Low risk	No loss to follow‐up or exclusion postrandomisation were reported.
Selective reporting (reporting bias)	Unclear risk	Not all of the primary outcomes of the review were reported.
Other bias	Low risk	Demographic variables were equally distributed in the groups.