| Methods |
Random allocation by a random‐number table. Blinding of some outcome assessments. |
| Participants |
115 women with spontaneous labour and delivery in Singapore.
Exclusion criteria: multiple pregnancy, any antenatal complications. |
| Interventions |
Carboprost trometamol* 125 mcg IM vs ergometrine‐oxytocin 0.5 mg IM. |
| Outcomes |
Blood loss, need for additional uterotonics, transfusion, haemoglobin levels, side‐effects.
Measurement of blood loss: blood and clots in the first 2 hours after delivery mopped with absorbent paper, sanitary pads collected for the next 22 hours, and then measured. |
| Notes |
Management of third stage: controlled cord traction after placenta separation.
3/115 (2.6%) women were excluded after randomisation. |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Random sequence generation (selection bias) |
Low risk |
"random number table." |
| Allocation concealment (selection bias) |
Low risk |
Adequate. |
| Blinding (performance bias and detection bias)
All outcomes |
Unclear risk |
Unclear if blinding occurred. |
| Incomplete outcome data (attrition bias)
All outcomes |
Low risk |
3 women were excluded as the births occurred before the blood loss measurement was set up. |
| Selective reporting (reporting bias) |
Unclear risk |
Not all of the primary outcomes of the review were reported. |
| Other bias |
Low risk |
"The parity, gestation, mode of delivery and the mean duration of first and second stage of labor were similar in the two groups." |
