| Methods |
Method of random allocation not stated. Double‐blinded trial. |
| Participants |
46 women at low risk for postpartum haemorrhage undergoing delivery by caesarean section in Arkansas, USA.
Exclusion criteria: hypertension, asthma, pre‐eclampsia, chorioamnionitis, multiple gestation or were receiving tocolytic agents. |
| Interventions |
Carboprost tromethamine* 0.125 mg intramyometrial vs oxytocin 20 IU intramyometrial. Both groups received 20 IU of oxytocin in 1 litre saline after delivery. |
| Outcomes |
Haematocrit change after delivery, blood loss not measured. |
| Notes |
Management of third stage: not applicable. |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Random sequence generation (selection bias) |
Unclear risk |
Unclear on how the adequate sequence generation was done. |
| Allocation concealment (selection bias) |
Low risk |
Adequate. |
| Blinding (performance bias and detection bias)
All outcomes |
Low risk |
Double‐blinded. |
| Incomplete outcome data (attrition bias)
All outcomes |
Low risk |
No losses to follow‐up. |
| Selective reporting (reporting bias) |
Unclear risk |
Not all of the primary outcomes of the review were reported. |
| Other bias |
Low risk |
The 2 groups were comparable. |
