USA 2005.

Methods	Randomised, placebo‐controlled. No mention of random‐number generation scheme. Allocation concealment by pharmacy‐assigned numbers to opaque vials containing either misoprostol tablets or oxytocin ampoules. Outcome assessments were blinded.
Participants	352 women undergoing caesarean section in Orlando, Florida, USA.
Interventions	Misoprostol 200 mcg buccal vs placebo at cord clamping. All women received 20 IU IV oxytocin in 1000 mL saline.
Outcomes	Blood loss, additional uterotonics. Blood loss was estimated following 'standard' procedures.
Notes	No loss to follow‐up.
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	No mention of random‐number generation scheme.
Allocation concealment (selection bias)	Low risk	Allocation concealment by pharmacy‐assigned numbers to opaque vials containing either misoprostol tablets or oxytocin ampoules.
Blinding (performance bias and detection bias) All outcomes	Low risk	"At no time before the data analysis were the assignments available to anyone but the pharmacy."
Incomplete outcome data (attrition bias) All outcomes	Low risk	No loss to follow‐up was reported.
Selective reporting (reporting bias)	Low risk	Primary outcomes of the review have been reported.
Other bias	Low risk	2 groups were comparable.