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. 2005 Jan 24;2005(1):CD000196. doi: 10.1002/14651858.CD000196.pub2

Pitts 1980.

Methods "Prospectively randomized" into three groups.
Participants Head injured adults admitted to hospital who were comatose on admission or who lapsed into coma for six hours or more.
Interventions
  1. Dexamethasone: initially 24mg IV per day, for a maximum of 7 days, tapering of for the last 5.

  2. Dexamethasone: initially 16mg IV daily, for a maximum of 7 days, tapering off for the last 5.

  3. Placebo.

Outcomes Glasgow Outcome Scale at 6 months. 
 Gastrointestinal bleeding. 
 Infections (signs of pneumonia, wound infection, urinary infection, blood culture, CSF culture).
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Low risk Adequate