Table 1.
PATHOLOGICAL FACTORS THAT PLAY A ROLE IN THE DEVELOPMENT OF VENTRICULAR FIBRILLATION | ||
---|---|---|
INHERITED | ACQUIRED | TEMPORARY CAUSES |
long QT syndrome | ischemic heart disease | sepsis |
short QT syndrome | chronic kidney disease | electrolyte disorders (especially K+ and Mg++) |
Brugada-syndrome | hypertension | electrocution |
catecholaminergic polymorphic ventricular tachycardia | cardiomyopathies | drug abuse (cocaine, methamphetamine) |
arrhythmogenic right ventricular dysplasia | acquired aortic disorders | provocative body posture in the case of structural heart disease |
single nucleotide polymorphisms (e.g. on 21q21 and 2q24.2 loci) | prior aborted cardiac death | drugs affecting QT interval: antimicrobial agents antipsychotics antidepressants antiarrhythmic drugs: amiodarone, sotalol, procainamide, quinidine, dofetilide, ibutilide |
J-point elevation syndromes | post-valvular surgery, post-TGA surgery or other heart surgeries | |
inherited structural heart diseases (tetralogy of Fallot, VSD, mitral prolapse, aortic disorders) | post-PCI or post-thrombolysis (reperfusion damage) |
VSD, ventricular septal defect, TGA, transposition of the great arteries, PCI, primary coronary intervention.