Figure 8.
HQH promotes translocation of GRα. Immunofluorescence showed GRα expression in Jurkat cells (A) treated with 4.3 mg/mL HQH and Nalm-6 cells (C) treated with 1.5 mg/mL HQH and control groups. HQH increased the expression of GRα in the nucleus and decreased the expression of GRα in the cytoplasm in Jurkat (B) and Nalm-6 cells (D). Western blotting was used to test the protein expression levels. β-actin and histone H3 were used as the internal control for cytosolic protein and nuclear protein, respectively. HQH – Huai Qi Huang; DEX – dexamethasone; GR – glucocorticoid receptor.