Liu 2005.
| Methods | Randomised clinical trial. |
| Participants | Pregnant women in preterm labour at less than 35 weeks' gestation. |
| Interventions | IM or IV vitamin K 10 mg per day for 2 to 7 days (44 infants), or no vitamin K (133 infants). Dexamethasone was given to both groups as per routine practice. |
| Outcomes | Vitamin K dependent coagulation factors in umbilical blood samples, PIVH. |
| Notes | Incidence of PIVH was 31.8% in the vitamin K group and 52.6% in the control group (P = 0.017). Incidence of severe PIVH was 2.3% in the vitamin K group and 12.0% in the control group (P = 0.057). |