| Methods |
Prospective randomised trial. |
| Participants |
36 mothers in preterm labour admitted to hospital. |
| Interventions |
17 women allocated to intramuscular vitamin K1, 19 allocated to placebo. |
| Outcomes |
Prothrombin time, activated partial thromboplastin time, factor II and protein C activity in cord blood samples |
| Notes |
|
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Adequate sequence generation? |
Low risk |
"random numbers table". |
| Allocation concealment? |
Unclear risk |
Not reported, but likely to have been pharmacy controlled. |
| Blinding?
All outcomes |
Low risk |
Placebo was used. |
| Incomplete outcome data addressed?
All outcomes |
Unclear risk |
Threre of the 19 women (16%) allocated to the placebo control group were subsequently excluded either because a delay in giving birth or missing data. |
| Free of selective reporting? |
Unclear risk |
No clinical or health outcomes reported. |
| Free of other bias? |
Low risk |
No apparent evidence of other bias. |
