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. 2020 Feb 26;2020(2):CD011961. doi: 10.1002/14651858.CD011961.pub2

NCT02225314.

Trial name or title Computer‐based cognitive training for individuals with PD‐MCI
Methods 3‐arm RCT of computerised auditory and accuracy training vs visual processing and working memory training vs active control (n = 25).
Participants People speaking English with a confirmed medical diagnosis of Parkinson's disease and meeting established criteria for MCI in PD (Litvan 2012), defined as individuals with performances of approximately 1 to −2 SDs below the mean on at least 2 tests within 5 cognitive domains assessed in clinical neuropsychological evaluations
People with dementia are excluded.
Interventions Treatment arm 1: computer‐based cognitive training known as Brain Fitness, which consists of 6 types of exercises that train auditory processing speed and accuracy
Treatment arm 2: computer‐based cognitive training known as InSight, a computer‐based cognitive training programme that consists of 5 types of exercises that train visual processing and working memory
60 minutes per day, 5 days a week
Active‐control training programme: computerised learning programme consisting of 5 programmes (i.e. Wright Brothers, History of Britain, Sister Wendy's American Collection, In Search of Shakespeare, and View the Cosmos) designed to improve knowledge about literature, art, and history.
Outcomes Primary outcome: per cent accuracy on cognitive training quizzes (Brain Fitness; auditory processing and accuracy tasks; InSight: visual processing and working memory tasks)
Secondary outcomes: PDQ‐39, California Verbal Learning Test‐II Long Delay Free Recall Scaled Score Change
Outcomes measured at 3 months.
Starting date 19 August 2014
Contact information sklageman@vcu.edu
Notes