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. 2000 Jul 24;2000(3):CD000212. doi: 10.1002/14651858.CD000212

Willkens 1984.

Methods Random allocation (exact method and concealment not stated)
Participants Psoriatic arthritis (DIP involvement/seronegative polyarthritis with psoriasis/arthrosis mutilans with psoriasis) 
 Multicentre recruitment 
 16 treatment/21 placebo 
 Corticosteroids not permitted
Interventions Oral methotrexate 7.5‐15 mg/wk versus identical placebo
Outcomes Tender joint count, joint swelling, physician assessment, grip strength, laboratory measures 
 duration 12 weeks
Notes 4 variables were included after discussion with the authors 
 11% dropout rate
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment (selection bias) Unclear risk B ‐ Unclear