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. 2020 Feb 26;15(2):e0229710. doi: 10.1371/journal.pone.0229710

Table 2. Sickle cell disease-related complications after hematopoietic stem cell transplantation (n = 16).

Complication Pre-HSCT
1 Year
Post- HSCT
1st Year
Post-HSCT
2nd Year
P Value
(Year 1 vs. pre-HSCT)
P Value
(Year 2 vs. pre-HSCT)
RBC Transfusion 2 (0–26) 8 (6–16) 0 (0–13) 0.4 0.005
Vaso-occlusive crisis 4 (1–29) 2 (0–8) 0 (0–37) 0.1 0.02
Acute chest syndrome 5 (31%) 1 (6%) 0 (0%) 0.07 0.02
Stroke 2 (13%) 0 (0%) 1 (6%) 0.1 0.6

13/16 had stable engraftment; 3/16 had secondary graft loss

HSCT, hematopoietic stem cell transplantation; RBC, red blood cell

Median (range) value provided