Table 2. Sickle cell disease-related complications after hematopoietic stem cell transplantation (n = 16).
Complication | Pre-HSCT 1 Year |
Post- HSCT 1st Year |
Post-HSCT 2nd Year |
P Value (Year 1 vs. pre-HSCT) |
P Value (Year 2 vs. pre-HSCT) |
---|---|---|---|---|---|
RBC Transfusion | 2 (0–26) | 8 (6–16) | 0 (0–13) | 0.4 | 0.005 |
Vaso-occlusive crisis | 4 (1–29) | 2 (0–8) | 0 (0–37) | 0.1 | 0.02 |
Acute chest syndrome | 5 (31%) | 1 (6%) | 0 (0%) | 0.07 | 0.02 |
Stroke | 2 (13%) | 0 (0%) | 1 (6%) | 0.1 | 0.6 |
13/16 had stable engraftment; 3/16 had secondary graft loss
HSCT, hematopoietic stem cell transplantation; RBC, red blood cell
Median (range) value provided