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. 2020 Feb 26;15(2):e0229534. doi: 10.1371/journal.pone.0229534

Fig 11. The impact of TMZ exposure period on DNA methylation in HaCaT cell line.

Fig 11

HaCaT cell culture was treated with the given single dose of TMZ (0.5, 1, 3, 5, 10 μM) and left for 1–7 days. The global DNA methylation was estimated after 1st, 2nd, 3rd, 4th, 5th, and 7th day of incubation. No significant change in DNA methylation is observed during time.