Table 2:

Relationship between amine, hydroxyl, and amine exchange and relaxation times from the literature spin-lock amplitudes (B₁) and static (B₀) field used in this study are included. The correlations are summarized in the table as positive (+), negative (−), or no correlation (↔). n/r signifies values not reported while empty cells were not measured in the study

Reference	Relaxation Trend with pH
	R1ρ	B1 (μT)	R2	R1	pH Range	B0 (T)
Kettunen et al.22	+	56.4	+		7.27–6.81 a	4.7
Magnotta et al.30	+	23.5			8.0–6.0b	4.7
Jokivarsi et al.38	+	40	+		7.31-n/r a	4.7
Mäkelä et al.39	+	25.1–27.7	+	-	8.0–5.5	4.7
Jin et al.17	+	2.9–94			7.5–6.0	9.4
Koenig et al.45				-	5.2–4.0	0.1
				-	7.4–6.5	0.1
				+	10–8.4	0.1
Meiboom et al.43			+	↔	8–6	0.7
			-	↔	10–8	0.7
Schilling et al.44			+	↔	7–6	2.4
			-	↔	7–8	2.4
Owusu et al.	+	4.7–18.8	+	+	8.0–6.0	3.0
	Relaxation Trend with Hydroxyl Protons				Concentration
Schuenke et al.42	+	5.0			5–20 mM	7.0
Jin et al.17	+	2.9–93.9			0–30 mM	9.4
Spear et al.29	+	1.2–235			0–200 mM	4.7,7.0
Owusu et al.	↔	4.7–18.8	↔	↔	0–40 mM	3.0
	Relaxation Trend with Amine Protons
Jin et al.17	-	2.9–93.9			0–20 mM b	9.4
Owusu et al.	↔	4.7–18.8	↔	↔	0–3.0 mM	3.0

^ain vivo data

^bagarose phantom.