Table 1. Demographics for hypertensive disorders of pregnancy cases and normotensive controls stratified by SDB status.
| HDP | Controls | |||||||
|---|---|---|---|---|---|---|---|---|
| All HDP* (n = 40) | SDB (n = 21) | No SDB (n = 19) | p | All Controls (n = 42) | SDB (n = 16) | No SDB (n = 26) | p | |
| Age (years) | 32.7 ± 4.5 | 33.3 ± 4.7 | 32.0 ± 4.3 | .38 | 33.1 ± 4.4 | 33.5 ± 3.9 | 32.9 ± 4.8 | .67 |
| Nulliparous | 26 (65.0%) | 14 (66.7%) | 12 (63.2%) | 1.0 | 20 (47.6%) | 9 (56.3%) | 11 (42.3%) | .53 |
| GDM | 8 (20.0%) | 5 (23.8%) | 3 (15.8%) | .70 | 9 (21.4%) | 4 (25.0%) | 5 (19.2%) | .71 |
| BMI first appt | 32.3 ± 7.3 | 33.8 ± 7.0 | 30.7 ± 7.4 | .18 | 32.6 ± 7.0 | 34.1 ± 7.8 | 31.8 ± 6.4 | .31 |
| BMI at PSG | 36.0 ± 7.0 | 38.1 ± 6.4 | 33.8 ± 7.0 | .047 | 36.3 ± 6.1 | 37.9 ± 6.8 | 35.3 ± 5.5 | .18 |
| Gestation at PSG (weeks) | 33.6 ± 3.5 | 34.0 ± 3.4 | 33.1 ± 3.6 | .41 | 33.0 ± 2.4 | 33.2 ± 2.3 | 32.9 ± 2.6 | .72 |
| RDI/hr | 5.2 (2.0, 14.8) | 14.3 (7.5, 37.7) | 1.9 (1.1, 3.1) | < .001 | 4.1 (2.2, 7.8) | 9.2 (7.5, 28.8) | 2.9 (1.3, 4.0) | < .001 |
| ODI≥3% overall | 2.1 (0.4, 10.1) | 6.0 (2.1, 36.7) | 1.0 (0.0, 1.8) | < .001 | 1.5 (0.6, 4.7) | 8.7 (1.1, 29.1) | 1.0 (0.2, 2.5) | .004 |
| PE diagnosis | 17 (42.5%) | 7 (33.3%) | 10 (52.6%) | .34 | - | - | - | - |
Values given as M ± SD, Mdn (IQR), or n (%). p value in table refers to SDB vs. No SDB groups
*No significant differences between HDP vs Controls
BMI measured at the first antenatal appointment was taken at a mean of 15.0 ± 2.6 weeks gestation. SDB = sleep-disordered breathing, HDP = hypertensive disorders of pregnancy, GDM = gestational diabetes mellitus, BMI = body mass index kg/m2, PSG = polysomnography, RDI = respiratory disturbance index, ODI = oxygen desaturation index.