Table 1.

Latent tuberculosis infection (LTBI) treatment regimens.

Regimen	Duration	Dose	Frequency	Total doses
Isoniazid plus rifapentine	3 months	Isoniazid 900 mg (15 mg/kg) Rifapentine: 750 mg if 32-50kg; 900 mg if > 50 kg	Once weekly a	12
Rifampin	4 months	600 mg (10 mg/kg)	Daily	120
Isoniazid plus rifampin	3–4 months	Isoniazid 300 mg (5mg/kg) Rifampin 600 mg (10 mg/kg)	Daily	90–120
Isoniazid	6–9 months	300 mg (5mg/kg) 900 mg (15 mg/kg)	Daily Twice-weekly b	180–270 52–76

^aIsoniazid and rifapentine weekly can be given as self-administered therapy (SAT) or direct observed therapy (DOT).⁵²

^bIsoniazid twice-weekly regimens must be provided by DOT.³⁴