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. 2019 Dec;22(12):1424–1431. doi: 10.22038/IJBMS.2019.13989

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This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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The effect of myricitrin and its SLN on the kidney histopathology and apoptosis. (A) Kidney histopathology (Hematoxylin & Eosin; ×40 magnification). (B) Kidney apoptosis (TUNEL; ×40 magnification). (a) Control. (b) Vehicle. (c) Diabetes. (d) Diabetes + myricitrin 1 mg/kg. (e) Diabetes + myricitrin 3 mg/kg. (f) Diabetes + myricitrin 10 mg/kg. (g) Diabetes + SLN containing myricitrin 1 mg/kg. (h) Diabetes + SLN containing myricitrin 3 mg/kg. (i) Diabetes + SLN containing myricitrin 10 mg/kg. Data are presented as mean±SEM; n=3; #P<0.05, ##P<0.01 and ###P<0.001 compared to the control, *P<0.05 and ***P<0.001 compared to the diabetes group. (Dia: Diabetes), (Myr: Myricitrin), (SLN: Solid lipid nanoparticle)