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. 2019 Dec;22(12):1468–1475. doi: 10.22038/IJBMS.2019.14068

Figure 8.

Figure 8

mRNA expressions of related genes of NPMSC cultured with different concentrations of simvastatin for 3 days. The Figures are described as means ± SD, n = 3. (A): aggrecan expression; (B): collagen type II expression; (C): HIF-1α expression; (D): VEGF expression; (E): GLUT-1 expression. *P<0.05 indicated significant difference compared to 0 μM group, #P<0.05 indicated significant difference compared to 0.01 μM group, &P<0.05 indicated significant difference compared to 0.1 μM group. NPMSC: Nucleus pulposus-derived mesenchymal stem cells, GLUT-1: Glucose transporter 1, VEGF: Vascular endothelial growth factor, HIF-1α: Hypoxia-inducible factor-1α .