Table 1. Table summarizing the amphid and cephalic sensory organ phenotypes of strains used in this study.
| Amphid sensory organ TEM phenotypes | |||||
|---|---|---|---|---|---|
| Mutant | Sex | Sensory compartment size | Matrix filled vesicles in sheath | EVs in pore | Reference |
| rab-28(tm2636) | Male | Not enlarged | Yes | Few vesicles/odd shaped particles observed surrounding MS | This work |
| rab-28(gk1040) | Hermaphrodite | Not enlarged | No | ND | Jensen et al., 2016 |
| RAB-28Q95L | Hermaphrodite | Enlarged | No | ND | Jensen et al., 2016 |
| RAB-28T49N | Hermaphrodite | Not enlarged | Yes | ND | Jensen et al., 2016 |
| bbs-8 | Male and hermaphrodite | Enlarged | Yes | Lots of EVs (in male) | This work |
| arl-6 | Hermaphrodite | Not enlarged | Yes | ND | This work |
| Male cephalic sensory organ TEM phenotypes | |||||
| Mutant | Sensory organ size | EVs in pore | Reference | ||
| rab-28(tm2636) | Enlarged | Yes, especially at the distal regions | This work | ||
| rab-28(gk1040) | ND | ND | N/A | ||
| RAB-28Q95L | ND | ND | N/A | ||
| RAB-28T49N | ND | ND | N/A | ||
| bbs-8 | Enlarged | Yes, surrounding all segments | This work | ||
| arl-6 | ND | ND | N/A | ||
| Other phenotypes | |||||
| Phenotype | rab-28(tm2636) | rab-28(gk1040) | arl-6 | bbs-8 | |
| PKD-2 localization in CEMs | Mislocalized | Normal (Jensen et al., 2016) | ND | ND | |
| CIL-7 localization in CEMs | Mislocalized | Mislocalized | Mislocalized | Mislocalized | |
| Environmental release of EVs from heads | Normal | Normal | Normal | Normal | |