(a) Plasma sCD30 in HIV-uninfected, untreated viraemic, ART-suppressed, CSF ‘escape’ and controller subgroups. (b) CSF sCD30 in HIV-uninfected, untreated viraemic, ART-suppressed, CSF ‘escape’ and controller subgroups. I indicates statistically significant comparison between group of interest and HIV-1 uninfected subgroup. II indicates statistically significant comparison between group of interest and viraemic subgroup. ART: antiretroviral therapy; CSF: cerebrospinal fluid