Table 2. Hazard ratios and 95% confidence intervals for T2DM risk according to plasma CD36 levelsa.
Variable | Tertiles of plasma CD36 | Continuous | |||
---|---|---|---|---|---|
T1b | T2b | T3b | Per SD (1.07 unit) | P linearc | |
No. cases/No. sub-cohort | 167/575 | 227/576 | 254/573 | ||
Median (range) | 0.26 (0.01–0.46) | 0.70 (0.46–0.99) | 1.54 (0.99–8.04) | ||
Model 1d | 1 | 1.30 (0.95–1.77) | 1.40 (1.03–1.90) | 1.11 (0.96–1.27) | 0.15 |
Model 2e | 1 | 1.22 (0.88–1.67) | 1.36 (1.00–1.86) | 1.10 (0.96–1.26) | 0.19 |
Model 2e+BMI | 1 | 1.16 (0.83–1.62) | 1.23 (0.87–1.73) | 1.05 (0.92–1.20) | 0.47 |
Model 2e+BMI+waist circumference | 1 | 1.17 (0.84–1.63) | 1.21 (0.88–1.68) | 1.05 (0.92–1.20) | 0.50 |
Model 2e+body fat percentage | 1 | 1.17 (0.84–1.65) | 1.20 (0.86–1.66) | 1.05 (0.91–1.20) | 0.52 |
T2DM, type 2 diabetes mellitus; SD, standard deviation; BMI, body mass index.
aHRs were obtained from Cox proportional hazard regression models stratified by sex, bTertiles were created based on the distribution in the random sub-cohort, cP values were calculated using the continuous CD36 variables, dModel 1 was adjusted for age, sex, eModel 2 was adjusted for age, sex, smoking status, alcohol consumption, physical activity, and education.