Table 1.
Bivariate and multivariate analysis of sodium level and clinical factors
| n (%) | Na (mEq/L) | Bivariate (P value) | Multivariate (P value) | ||
| Age1 | < 50 yr | 150 (16) | 138.3 | 0.0001 | 0.821 |
| 50-69 yr | 487 (53) | 136.6 | |||
| ≥ 70 yr | 283 (31) | 135.8 | |||
| Glucose1 | Normal (< 115 mg/dL) | 392 (44) | 137.6 | 0.0001 | 0.127 |
| Elevated (≥ 115 mg/dL) | 501 (56) | 135.7 | |||
| Illness severity | No infectious manifestations | 403 (44) | 138.7 | 0.0001 | 0.0001 |
| SIRS | 196 (21) | 136.7 | |||
| Severe | 154 (17) | 134.7 | |||
| Sepsis/MODS | 167 (18) | 133.2 | |||
| Bacterial location | None/sterile | 396 (45) | 138.3 | 0.0001 | 0.023 |
| Gallstone only | 60 (7) | 137.2 | |||
| Bile | 338 (38) | 135.4 | |||
| Blood | 85 (10) | 133.1 | |||
| Gangrenous changes | None | 732 (80) | 137.3 | 0.0001 | 0.002 |
| Gangrene | 188 (20) | 133.8 | |||
| Charlson Co-Morbidity index1 | 0-2 | 518 (57) | 137.4 | 0.0001 | 0.001 |
| 3-4 | 261 (29) | 136.2 | |||
| 5 or more | 140 (14) | 134.6 |
1
Analyzed as a continuous variable. MODS: Multisystem organ dysfunction syndrome; SIRS: Systemic inflammatory response syndrome; Gangrenous changes: Gangrenous cholecystitis, gallbladder perforation, abscess, necrotizing pancreatitis.