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. 2020 Feb 20;11:21. doi: 10.3389/fphar.2020.00021

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Copyright © 2020 Bi, Li, Li, Li, Lin, Yao, Li, Xu, Hu, Zhang, Liu and Xu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of Se-PM (0.5 mg/mL) on cell apoptosis in N2a-sw cells. (A, B) Immunofluorescence analysis of the mitochondrial membrane potential (A) and statistical analysis (B). (C, D) Immunofluorescence analysis of cytochrome c release (C) and statistical analysis (D). (E, F) Protein expression levels of Bax/Bcl-2, detected by Western blot analysis (E) and statistical analysis (F). Indicates significant differences between the N2a-sw cells and N2a cells, ^##p < 0.01. *Indicates significant differences between the Se-PM-treated groups and control in N2a-sw cells, * p < 0.05. ** p < 0.01. Scale bar = 20 μm.