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. 2020 Feb 26;10:3514. doi: 10.1038/s41598-020-60578-2

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Proteins from the group “Protein UP–mRNA NS” demonstrate reduced enrichment of motifs associated with protein degradation. (a) The physicochemical properties of proteins belonging to the group “Protein UP–mRNA NS” and those of all other proteins detected in the present study. Data are expressed as the median and interquartile range. (b) Relevance of differences in motif enrichment among these protein groups (the lower the rank [dark red], the higher the relevance). Because both the motif abundance (frequency) and the adjusted odds ratio among the groups explain differences in protein regulation (or mRNA translation initiation), the relevance of differences in motif enrichment among the protein groups was calculated based on these parameters and expressed as a mean rank.