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. 2020 Feb 26;10:3472. doi: 10.1038/s41598-020-59458-6

Table 3.

Comparison of the cognitive assessment variables of the participants according to their PA level.

n Low (n = 4118) Moderate (n = 1297) High (n = 1459) p for trend
MMSE test Temporal orientation 6669 Model 1 4.86 (4.85–4.87) 4.88 (4.86–4.91) 4.87 (4.85–4.9) NS
Model 2 4.9 (4.81–4.99) 4.92 (4.83–5.01) 4.88 (4.79–4.98) NS
Place orientation 6669 Model 1 4.96 (4.95–4.97) 4.96 (4.94–4.97) 4.96 (4.95–4.98) NS
Model 2 4.94 (4.89–4.99) 4.94 (4.89–4.99) 4.93 (4.88–4.98) NS
Immediate recall 6670 Model 1 2.99 (2.98–2.99) 2.98 (2.97–2.99) 2.99 (2.98–3) NS
Model 2 3 (2.96–3.04) 3 (2.96–3.04) 3 (2.96–3.04) NS
Calculation 6670 Model 1 4.49 (4.45–4.52) 4.5 (4.44–4.56) 4.53 (4.47–4.59) NS
Model 2 4.51 (4.28–4.73) 4.49 (4.26–4.71) 4.49 (4.26–4.72) NS
Delayed recall 6670 Model 1 2.23 (2.2–2.26) 2.22 (2.18–2.27) 2.23 (2.18–2.28) NS
Model 2 2.25 (2.06–2.44) 2.25 (2.05–2.44) 2.24 (2.05–2.44) NS
Language 6650 Model 1 8.67 (8.65–8.69) 8.66 (8.62–8.69) 8.68 (8.64–8.71) NS
Model 2 8.7 (8.57–8.83) 8.68 (8.55–8.81) 8.7 (8.56–8.83) NS
Total MMSE score 6650 Model 1 28.2 (28.14–28.26) 28.21 (28.11–28.32) 28.27 (28.16–28.37) NS
Model 2 28.31 (27.92–28.7) 28.28 (27.88–28.68) 28.25 (27.85–28.65) NS
CDT score 6652 Model 1 5.95 (5.91–5.99) 5.93 (5.86–6) 5.9 (5.83–5.97) NS
Model 2 6.03 (5.77–6.3) 6.03 (5.76–6.3) 6.01 (5.74–6.28) NS
TMT test Total time A 6703 Model 1 53.5 (52.65–54.35) 52.66 (51.19–54.13) 51.41 (49.91–52.92) NS
Model 2 48.28 (42.58–53.98) 47.97 (42.16–53.79) 45.82 (39.99–51.65) NS
Total time B 6784 Model 1 136.59 (134.15–139.03) 133.04 (128.81–137.26) 133.48 (129.16–137.81) NS
Model 2 123.82 (107.36–140.28) 126.1 (109.31–142.89) 125.46 (108.63–142.3) NS
COWAT test Phonetic fluency 6723 Model 1 12.11 (11.97–12.25) 12.4 (12.16–12.64) 12.77 (12.53–13.02) <0.001
Model 2 12.6 (11.7–13.5) 12.67 (11.75–13.59) 12.89 (11.97–13.81) NS
Semantic fluency 6723 Model 1 15.97 (15.83–16.12) 16.01 (15.75–16.26) 16.59 (16.33–16.85) 0.003
Model 2 16.88 (15.9–17.87) 16.69 (15.69–17.7) 17.21 (16.21–18.22) NS
DS test Direct numeric series score 5345 Model 1 8.67 (8.59–8.75) 8.82 (8.67–8.97) 8.97 (8.82–9.12) 0.032
Model 2 8.58 (7.98–9.19) 8.55 (7.93–9.17) 8.55 (7.93–9.17) NS
Direct span 2213 Model 1 5.47 (5.36–5.57) 5.51 (5.38–5.65) 5.54 (5.4–5.68) NS
Model 2 5.61 (5.15–6.07) 5.6 (5.13–6.06) 5.64 (5.18–6.11) NS
Inverse numeric series score 5347 Model 1 5.05 (4.97–5.12) 5.14 (5–5.27) 5.18 (5.05–5.32) NS
Model 2 4.82 (4.29–5.35) 4.82 (4.28–5.36) 4.72 (4.18–5.26) NS
Inverse Span 2200 Model 1 3.68 (3.59–3.78) 3.67 (3.55–3.79) 3.78 (3.65–3.91) NS
Model 2 3.76 (3.36–4.16) 3.74 (3.33–4.14) 3.85 (3.44–4.26) NS

COWAT = Controlled Oral Word Association Test; DS = Digit Span test; MMSE = Mini-mental State Examination test; TMT = Trail Making Test.

NS = non significant.

Light = light-moderate PA activities but not every week; Moderate = moderate PA activities ≤150 min/week or vigorous PA activities ≤75 min/week; High = >150 min/week of moderate PA activities or >75 min/week of vigorous activities.

Mean ± (95% confidence interval).

Model 1: ANCOVA adjusted for age, sex and recruitment center.

Model 2: ANCOVA adjusted for age, sex, recruitment center, smoking status, adherence to er-MedDiet, BMI, civil status, educational level, sleep hours, working status, TV hours and prevalence of type 2 diabetes, depression, hypertension and cancer.

Significant p values in bold.