Table 1.
Challenge Dose (ffu) | Zika vRNA (log10 copies/mL) | |||||||
---|---|---|---|---|---|---|---|---|
Day 1 | Day 2 | Day 3 | Day 4 | Day 5 | Day 6 | Day 7 | Day 8 | |
104 | UD | <LLOQ | 4.5 | 4.9 | 4.8 | 4.6 | 3.5 | 2.9 |
UD | UD | 4.6 | 4.9 | 5.6 | 5.4 | UD | <LLOQ | |
105 | UD | 3.3 | 4.6 | 4.8 | 4.3 | 3.8 | UD | UD |
UD | 3.8 | 4.3 | 5.0 | 5.0 | 4.0 | UD | UD |
Zika vRNA (log10 copies/mL) per day post-challenge for each individual macaque. Zika vRNA for individual macaques was not quantified in the 104 ffu dose after day 8 or the 105 ffu challenge dose group after day 6 post-challenge. UD = Undetected. <LLOQ = detected vRNA was below the assay lower limit of quantitation.