Table 1.
Antimicrobial activities of delafloxacin, levofloxacin, and moxifloxacin tested against intravitreal Staphylococcus isolates
| Organism | Rates of resistance | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| All isolates | MIC90a | MSSAb | MIC90 | MSSEc | MIC90 | MRSAd | MIC90 | MRSEe | MIC90 | |
| Levofloxacin | 60% (26/43) | 8.0 | 50% (2/4) | -- | 60% (6/10) | 8.0 | 83% (5/6) | -- | 54% (13/24) | 8.0 |
| Moxifloxacin | 50% (22/44) | 8.0 | 50% (2/4) | -- | 55% (6/11) | 8.0 | 83% (5/6) | -- | 54% (13/24) | 8.0 |
| Delafloxacin | 12% (12/43) | 1.0 | 0% (0/4) | -- | 27% (3/11) | 0.8 | 33% (2/6) | -- | 25% (6/24) | 0.8 |
aMIC90, minimum inhibitory concentration at which growth of 90% of organisms is inhibited, expressed in micrograms per milliliter (μg/ml), which were only calculated for microbes with more than 10 isolates
bMSSA, methicillin-sensitive S. aureus
cMRSA,methicillin-resistant S. aureus
dMSSE, methicillin-sensitive S. epidermidis
eMRSE, methicillin-resistant S. epidermidis