Figure 2.
Motor function declines slightly faster in female SOD1G37R/YFP mice. A, B, Body weight (A) and all-limb grip strength (B) curves of male and female (light and dark colors, respectively) WT/YFP and SOD1G37R/YFP mice (blue and red, respectively) during the symptomatic stages (WT female: N = 14; WT male: N = 6; SOD1 female: N = 8; SOD1 male: N = 12). Data are presented as mean ± SEM. Main effects and interactions are reported in Table 1 and in the text. Asterisks and crosses represent biologically relevant statistically significant differences in the post hoc test (Tukey’s multiple comparisons). Asterisks represent differences compared with the other genotype, while crosses represent differences compared with the other sex; */†p < 0.05, **/††p < 0.01, ***/†††p < 0.001, ****/††††p < 0.0001.