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miR-122 represses Slc1a5 expression by direct targeting.A. qRT-PCR analysis of Slc1a5 mRNA expression after miR-122 mimic or NC mimic expression in HCC cells. B. miR-122 seed matches in Slc1a5 predicted by TargetScan. C. Validation of two of three sites in Slc1a5-3′-UTR as miR122 targets by luciferase assay driven by wild type (WT) and mutant Slc1a5 3′-UTR co-transfected with miR-122 mimic or NC mimic. * and **denote P values of ≤0.05 and 0.01, respectively (n = 3–4).
