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. 2020 Feb 20;8:39. doi: 10.3389/fchem.2020.00039

Figure 9.

Figure 9

Potential lysosome-targeting CL Probe detects ebselen-sensitive LPS and IFN-γ generated ONOO in murine macrophages. RAW 264.7 macrophages were stimulated with LPS (1 μg/ml) for 4 h and IFN-γ (50 ng/ml) and where indicated treated for 1 h with ebselen (50 μM). CL (20 μM), was incubated for 30 min. Blue channel: λex = 405 nm, λem = 420–460 nm. Scale bar: 20 μm. Magnification x60. n = 3.