FIG. 1.

Comparison of global network properties between TLE subjects and HCs in (A) clustering coefficient, (B) average shortest path length, and (C) global efficiency as a function of network sparsity. Blue circle line shows difference between mean TLE and HCs for each measurement at each specific network sparsity. Although Δ = 0 indicates no difference, Δ > 0/Δ < 0 indicates an increase/decrease in the network density of TLE subjects relative to HCs. The blue dash line shows 95% confidence interval of the null distribution of number between group difference obtained from 100,000 permutation tests at each density value. Asterisks (red) indicate significant between-group differences (p < 0.05). HCs, healthy controls; TLE, temporal lobe epilepsy.