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. 2020 Feb 27;2020(2):CD000451. doi: 10.1002/14651858.CD000451.pub3

Comparison 8. Amniotic membranes sweeping versus no treatment/sham (Primiparae/Multiparae).

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Spontaneous onset of labour 17 3170 Risk Ratio (M‐H, Random, 95% CI) 1.21 [1.08, 1.34]
1.1 Parity ‐ Multiparae 2 361 Risk Ratio (M‐H, Random, 95% CI) 1.05 [0.92, 1.20]
1.2 Parity ‐ Primiparae 3 447 Risk Ratio (M‐H, Random, 95% CI) 1.41 [1.15, 1.72]
1.3 Parity ‐ unknown 12 2362 Risk Ratio (M‐H, Random, 95% CI) 1.20 [1.05, 1.38]
2 Induction of labour 17 3271 Risk Ratio (M‐H, Random, 95% CI) 0.72 [0.56, 0.92]
2.1 Parity ‐ Primiparae 5 600 Risk Ratio (M‐H, Random, 95% CI) 0.35 [0.14, 0.85]
2.2 Parity ‐ Multiparae 2 303 Risk Ratio (M‐H, Random, 95% CI) 0.87 [0.52, 1.47]
2.3 Parity ‐ unknown 11 2368 Risk Ratio (M‐H, Random, 95% CI) 0.78 [0.58, 1.06]
3 Caesarean section 32 5499 Risk Ratio (M‐H, Random, 95% CI) 0.93 [0.83, 1.03]
3.1 Primiparae 4 493 Risk Ratio (M‐H, Random, 95% CI) 0.96 [0.41, 2.21]
3.2 Multiparae 4 585 Risk Ratio (M‐H, Random, 95% CI) 0.75 [0.48, 1.19]
3.3 Parity ‐ unknown 25 4421 Risk Ratio (M‐H, Random, 95% CI) 0.92 [0.79, 1.07]
4 Spontaneous vaginal birth 26 4538 Risk Ratio (M‐H, Random, 95% CI) 1.03 [0.99, 1.07]
4.1 Primiparae 3 424 Risk Ratio (M‐H, Random, 95% CI) 1.02 [0.89, 1.18]
4.2 Multiparae 4 585 Risk Ratio (M‐H, Random, 95% CI) 1.20 [0.82, 1.75]
4.3 Parity ‐ unknown 20 3529 Risk Ratio (M‐H, Random, 95% CI) 1.03 [0.99, 1.07]
5 Maternal death or serious morbidity 17 2749 Risk Ratio (M‐H, Random, 95% CI) 0.83 [0.57, 1.20]
5.1 Parity ‐ Primiparae 2 169 Risk Ratio (M‐H, Random, 95% CI) 0.0 [0.0, 0.0]
5.2 Parity ‐ Multiparae 0 0 Risk Ratio (M‐H, Random, 95% CI) 0.0 [0.0, 0.0]
5.3 Parity ‐ unknown 15 2580 Risk Ratio (M‐H, Random, 95% CI) 0.83 [0.57, 1.20]
6 Neonatal death or serious neonatal perinatal morbidity 18 3696 Risk Ratio (M‐H, Random, 95% CI) 0.83 [0.59, 1.17]
6.1 Parity ‐ Primiparae 1 100 Risk Ratio (M‐H, Random, 95% CI) 0.57 [0.18, 1.83]
6.2 Parity ‐ Multiparae 0 0 Risk Ratio (M‐H, Random, 95% CI) 0.0 [0.0, 0.0]
6.3 Parity ‐ unknown 17 3596 Risk Ratio (M‐H, Random, 95% CI) 0.86 [0.60, 1.23]