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. 2020 Feb 27;2020(2):CD000451. doi: 10.1002/14651858.CD000451.pub3

Sharma 2012.

Trial name or title Induction of labour in women with previous one caesarean section. Prosprctive double blind randomised control trial comparing the effect of mifepristone with sweeping stretching and trans‐cervical Folley's catheterization.
Methods  
Participants Pregnant females, age 18 to 40 years of age with a singleton pregnancy, previous 1 low segment caesarean section, no other uterine scar or previous rupture. Gestation beyond 40 weeks and cephalic presentation.
Interventions Group 1: no details reported in trial report.
Group 2: women in this group will have initial assessment of Bishop score by senior consultant and receive 400 mg of mifepristone at 40 weeks 5 days gestation and will be re‐assessed at 24 hours and 48 hours later by senior consultant (blinded to the group of patient). If patient goes into labour this will be accounted for. Any time if Bishop score is more than 6, amniotomy will be performed followed by oxytocin infusion. If Bishop score is still less than 6 after 48 hours they will be induced with oxytocin.
Group 3: women in this group will be inserted with trans‐cervical catheter after initial cervical assessment (Foley catheter number 16 filled with 30 mL of normal saline) at 40 weeks 5 days gestation and will be advised to pull the catheter every 20 minutes for 1 minute each. Foleys catheter will be removed after 6 hours, if it does not come out on its own. These women will be re‐assessed vaginally after 24 hours or earlier if catheter comes out, if Bishop score is more than 6, amniotomy will be performed followed by oxytocin infusion otherwise re‐assessed at 48 hours and induced with oxytocin.
Outcomes
  1. To compare the proportion of women entering labour after use of mifepristone alone as compared to sweeping stretching of cervix or use of trans‐cervical Foley’s catheter.

  2. Proportion of women vaginally delivered in each group

  3. Proportion of women with caesarean section in each group

  4. Duration of labour in women in each group

  5. Need and amount of oxytocin required in each group

  6. Proportion of women with scar dehiscence/rupture in each group

  7. Neonatal outcomes

Starting date States "open to recruitment" 11 April 2017
Contact information DR RPGMC KANGRA Aat TANDA (HP) Proff and Head, OBG, DR
 RPGMC KANGRA AT TANDA (HP)
 Kangra
 HIMACHAL PRADESH
 176001
 India
Tel: 91‐9218925471 Email: sureshsverma@gmail.com
Notes Emailed trial authors for further information on membrane sweeping intervention. No reply to date.