. 2020 Jan 15;10(1):e033495. doi: 10.1136/bmjopen-2019-033495

Table 4.

Primary analysis excluding deaths. Incremental cost-effectiveness ratios (ICERs) and probability of cost-effectiveness of TKR plus non-surgical treatment versus non-surgical treatment alone for each scenario

Analysis	Incremental cost	95% CI	Incremental effect	95% CI	ICER	Probability of cost-effectiveness at 22 665 Euros
Analysis	Euros	95% CI	QALY	95% CI	Euros/QALY	%
Base-case	6070	1857 to 10 283	0.186	0.078 to 0.294	32 611	23.2
Scenario 1	4640	−200 to 9480	0.233	0.088 to 0.378	19 917	58.3
Scenario 2	4481	−668 to 9629	0.242	0.095 to 0.390	18 497	61.9

Base-case=adjusted for age, sex and baseline value; Scenario 1=unadjusted; Scenario 2=unadjusted and without imputation of missing values.

QALY, quality-adjusted life year; TKR, total knee replacement.