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. 2020 Feb 17;10(2):e034403. doi: 10.1136/bmjopen-2019-034403

Table 1.

Inclusion and exclusion criteria

Inclusion criteria Exclusion criteria
  • Age ≥18 years

  • Suspected NSTE-ACS

  • Symptom duration of at least 2 hours

  • Modified HEAR(T) score ≤3

  • Provided written informed consent

  • ST-segment elevation

  • Suspected non-cardiac cause of the symptoms requiring evaluation at the emergency department

  • Comatose state, defined as a GCS score <8

  • Known cognitive impairment

  • Pregnancy

  • Cardiogenic shock, defined as systolic blood pressure <90 mm Hg, heart rate >100 bpm and peripheral oxygen saturation <90%

  • Syncope

  • Signs of heart failure

  • Heart rhythm disorders and second-degree or third-degree atrioventricular block

  • Known end-stage renal disease (dialysis and/or MDRD <30 mL/min)

  • Suspected aortic dissection or pulmonary embolism

  • Confirmed AMI, PCI or CABG <30 days prior to inclusion

  • Communication issues with the patient and/or language barrier

  • Decision of a present general practitioner to evaluate the patient at the emergency department

  • Decision of the consultant cardiologist to evaluate the patient at the emergency department

  • Any significant medical or mental condition, which in the investigator’s opinion may interfere with optimal participation in the study

AMI, acute myocardial infarction; CABG, coronary artery bypass grafting; GCS, Glasgow Coma Scale; MDRD, Modification of Diet in Renal Disease formula; NSTE-ACS, non–ST-segment elevation acute coronary syndrome; PCI, percutaneous coronary intervention.