Symptom reporting in the antecedent cohort. The percentage of participants reporting symptoms per day for each of the collected symptoms per group: TIV – Spn non-colonised (n = 38, black circles and solid line), TIV – Spn colonised (n = 23, black triangles and dashed line), LAIV – Spn non-colonised (n = 29, grey circles and solid line), LAIV – Spn colonised (n = 24, grey triangles and dashed line). Day of vaccination and Spn inoculation are depicted. Spn = S. pneumoniae.