Table 2.
Cargo interactors of TMED proteins.
| TMED protein | Cargo | Interaction location | Experimental system |
|---|---|---|---|
| TMED1 | IL1RL1 (ST2L/IL-33R) | ER, cis-Golgi | Cell culture |
| TMED2 | AGR2 | n/a | Cell culture and mouse |
| GCGR | n/a | Cell culture | |
| TMEM173 (MITA) | ER | Cell culture | |
| Wga | ER and Golgi | Drosophila | |
| CD59a | ER | Cell culture | |
| Folate receptora | ER | Cell culture | |
| Gas1pa | ER | Yeast | |
| F2R (PAR-1) | Golgi | Cell culture | |
| F2RL1 (PAR-2)a | Golgi | Cell culture | |
| P2YR (1,2,4,11) | Golgi | Cell culture | |
| OPRM1 (MOR1B) | Golgi | Cell culture | |
| CASR | ER | Cell culture | |
| SM-18 | COPI vesicles | Cell culture | |
| TMED9 | PS1-NTFa | n/a | Cell culture |
| NCTa | n/a | Cell culture | |
| APH-1a | n/a | Cell culture | |
| PEN-2a | n/a | Cell culture | |
| TMED10 | TGFBR2 | Cell membrane | Cell culture |
| TGFBR1 (ALK5) | Cell membrane | Cell culture |
a Also interacts with TMED10.
ER = endoplasmic reticulum; n/a = not applicable.