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. Author manuscript; available in PMC: 2020 Feb 27.
Published in final edited form as: Nature. 2018 Jul 18;560(7716):102–106. doi: 10.1038/s41586-018-0353-2

Extended Data Figure 2: Metabolite analysis of the acute response of BAT to β3-adrenergic stimulus in vivo by CL.

Extended Data Figure 2:

a, Rapid depletion of BAT triacylglycerol (TAG) species following i.v. injection of 1 mg/kg CL. b, Depletion of BAT diacylglycerol (DAG) species following i.v. injection of CL. c, Accumulation of free fatty acid species and acyl-carnitine species in BAT following i.v. injection of CL. d, Abundance of TCA cycle metabolites in BAT following i.v. β-adrenoreceptor agonism with 1 mg/kg isoproterenol or 1 mg/kg CL (n = 5; CL, iso n = 4). c, one-way ANOVA; d, two-sided t-test; data are mean of biologically independent samples ± s.e.m.