Table 4.

[Ca²⁺]i oscillation for control, TRPV4-KD, Piezo1-KD, and Piezo2-KD stimulated with 8% CTS stimulation (mean ± standard deviation).

	8% CTS control (n = 47)	8% CTS TRPV4-KD (n = 38)	8% CTS Piezo1-KD (n = 41)	8% CTS Piezo2-KD (n = 42)
[Ca2+]i response rates (%)	20.12 ± 1.72	13.04 ± 1.16 ↓	21.45 ± 1.87	20.18 ± 1.99
Amplitude	7.07 ± 0.51	3.01 ± 0.27 ↓	6.64 ± 0.67	6.42 ± 0.59
Frequency (Peaks/min)	0.20 ± 0.01	0.17 ± 0.01 ↓	0.20 ± 0.02	0.19 ± 0.02

Note: Cell numbers examined for [Ca²⁺]_i oscillation were 47 cells (control), 38 cells (TRPV4-KD), 41 cells (Piezo1-KD), and 42 cells (Piezo2-KD) for 8% CTS, respectively. Data are represented as the mean ± standard deviation of three independent experiments.

TRPV4: transient receptor potential vanilloid 4; CTS: cyclic tensile strains; KD: knockdown.