Table 5.

[Ca²⁺]i oscillation for control, TRPV4-KD, Piezo1-KD, and Piezo2-KD stimulated with 13% CTS stimulation (mean ± standard deviation).

	13% CTS control (n = 37)	13% CTS TRPV4-KD (n = 40)	13% CTS Piezo1-KD (n = 33)	13% CTS Piezo2-KD (n = 34)
[Ca2+]i response rates (%)	21.47 ± 1.82	20.85 ± 1.86	15.33 ± 1.22 ↓	14.96 ± 1.37 ↓
Amplitude	7.86 ± 0.66	7.69 ± 0.71	2.87 ± 0.24 ↓	3.63 ± 0.31 ↓
Frequency (Peaks/min)	0.20 ± 0.01	0.19 ± 0.01	0.16 ± 0.01 ↓	0.15 ± 0.01 ↓

Note: Cell numbers examined for [Ca²⁺]_i oscillation were 37 cells (control), 40 cells (TRPV4-KD), 33 cells (Piezo1-KD), and 34 cells (Piezo2-KD) for 13% CTS, respectively. Data are represented as the mean ± standard deviation of three independent experiments.

TRPV4: transient receptor potential vanilloid 4; CTS: cyclic tensile strains; KD: knockdown.