Table 2.

Medication Use in Intervals 1 (6 months after diagnosis) and 3 (1–1.5 years after diagnosis)

	Interval 1 (First 6 months)					Interval 3 (1–1.5 years)
Characteristics	Overall	1st Pulse Rate Decile	5th Pulse Rate Decile	10th Pulse Rate Decile	p-value	Overall	1st Pulse Rate Decile	5th Pulse Rate Decile	10th Pulse Rate Decile	p-value
	N = 44,093	(47–59 bpm)	(72–75 bpm)	(97–117 bpm)		N = 44,093	(47–59 bpm)	(72–75 bpm)	(97–117 bpm)
		n = 6116	n = 4753	n = 2269			n = 6433	n = 5094	n = 2214
ACE Inhibitor or ARB, %	31,716 (77.2%)	4808 (78.6%)	3626 (76.3%)	1741 (76.7%)	0.0007	28,970 (67.0%)	4523 (70.3%)	3433 (67.4%)	1349 (60.9%)	<.0001
Aldosterone Antagonists, %	6574 (16.0%)	878 (14.4%)	789 (16.6%)	410 (18.1%)	<.0001	6374 (14.8%)	838 (13.0%)	778 (15.3%)	308 (13.9%)	<.0001
Beta blocker, %	33,407 (81.3%)	5177 (84.6%)	3861 (81.20%)	1696 (74.7%)	<.0001	31,735 (73.4%)	5031 (78.2%)	3804 (74.7%)	1373 (62.0%)	<.0001
Calcium channel blocker, %	8626 (21.0%)	1536 (25.1%)	945 (19.9%)	404 (17.8%)	<.0001	7861 (18.2%)	1442 (22.4%)	890 (17.5%)	353 (15.9%)	<.0001
Statins, %	29,996 (73.00%)	4644 (75.9%)	3488 (723.4%)	1480 (65.2%)	<.0001	28,950 (67.0%)	4579 (71.2%)	3401 (66.8%)	1253 (56.6%)	<.0001
Nitrates, %	8435 (20.5%)	1426 (23.3%)	1935 (19.7%)	397 (17.5%)	<.0001	7164 (16.6%)	1221 (19.0%)	830 (16.3%)	274 (12.4%)	<.0001
Loop Diuretic, %	20,508 (49.9%)	2847 (48.25%)	2394 (50.4%)	1287 (56.7%)	<.0001	18,575 (43.0%)	2642 (41.1%)	2243 (44.0%)	962 (43.5%)	0.0084
Thiazides, %	5838 (14.2%)	939 (15.4%)	666 (14.0%)	323 (14.2%)	0.1137	4670 (10.8%)	785 (12.2%)	540 (10.6%)	2055 (9.3%)	0.005
Anticoagulant, %	4017 (9.8%)	639 (10.4%)	456 (9.6%)	241 (10.6%)	0.1794	3715 (8.6%)	644 (10.0%)	407 (8.0%)	189 (8.5%)	<.0001
Digoxin, %	4410 (10.7%)	598 (9.8%)	518 (10.9%)	287 (12.6%)	0.0105	4176 (9.7%)	507 (7.9%)	511 (10.0%)	234 (10.6%)	<.0001