Telimaa 1988(a).
Methods | Random allocation. Method not described. | |
Participants | Endometriosis, all stages, at laparoscopy; infertility duration unspecified. | |
Interventions | Provera 100 mg daily for 6 months, n=17 patients randomised and included versus placebo daily for 6 months, n=14 patients randomised and included. | |
Outcomes | Clinical pregnancy, diagnosis not defined; data reported by stage of disease. | |
Notes | Up to 30 months post‐treatment follow up; 3‐arm trial; approximately 1/3 patients in each arm received treatment or placebo after conservative surgery. Pregnancy data not separable for medical treatment alone. Co‐intervention with electrocautery at laparoscopy in 9 women and clomiphene in 11 women, but these treatments were evenly distributed across allocation groups. ITT analysis done. Funding: drugs supplied by Farmos Group Ltd Turku, Finland. Note that this is the same study as Telimaa 1988 (b). |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Adequate sequence generation? | Unclear risk | 'Randomly allocated' no further details provided. |
Allocation concealment? | Unclear risk | Unclear; no details provided. |
Blinding? All outcomes | High risk | No details of blinding. |
Incomplete outcome data addressed? All outcomes | Low risk | Data reported on all women. |
Free of selective reporting? | High risk | Not followed up to live birth. |