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. 2019 Oct 15;47(12):5977–5985. doi: 10.1177/0300060519879336

Table 1.

Demographic and clinical characteristics of patients with carbapenem-resistant Acinetobacter baumannii (CRAB) bacteremia treated with colistin vs. colistin plus meropenem.

Patient characteristics Colistin (n = 40) Colistin plus meropenem (n = 31) p
Age, years 64.57 ± 16.24 70.06 ± 12.01 0.12
Sex, male 22 (55.0%) 20 (64.5%) 0.41
Comorbid condition
Diabetes mellitus 16 (40.0%) 12 (38.7%) 1.00
Cardiovascular disease 8 (20.0%) 9 (29.0%) 0.37
Chronic lung disease 11 (27.5%) 9 (29.0%) 0.88
Renal impairment 12 (30.0%) 10 (32.3%) 0.83
Chronic liver disease 8 (20.0%) 3 (9.7%) 0.32
Cerebrovascular disease 17 (42.5%) 13 (41.9%) 0.96
Malignancy 6 (15.0%) 9 (29.0%) 0.15
Charlson Comorbidity Index 3.20 ± 1.77 3.32 ± 1.44 0.75
Pitt bacteremia score 4.05 ± 2.51 3.93 ± 2.30 0.84
Steroid/immunosuppressant use 5 (12.5%) 8 (25.8%) 0.15
Recent surgery 11 (27.5%) 10 (32.3%) 0.66
CVC 36 (90.0%) 28 (90.3%) 0.96
Type of infection
Pneumonia 15 (37.5) 16 (51.6) 0.33
 CRI 17 (42.5%) 10 (32.3) 0.46
 SSTI 4 (10.0) 3 (9.7) 1.00
 IAI 2 (5.0) 1 (3.2) 1.00
 UTI 0 (0) 1 (3.2) 0.43
 PB 1 (2.5) 0 (0) 1.00
 CNS infection 1(2.5) 0 (0) 1.00
ABs before colistin administration 15 (37.5) 5 (16.1) 0.06
ABs during colistin and/or meropenem administration 8 (20.0) 3 (9.7) 0.32

Data are presented as mean ± standard deviation, SD for continuous variables and as n (%) of patient s for categorical variables. CVC, central venous catheter; CRI, central line associated infection; UTI, urinary tract infection; SSTI, skin and soft tissue infection; IAI, intra-abdominal infection; PB, primary bacteremia; CNS, central nervous system, ABs, antibiotics other than colistin or meropenem.